CTDSP1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CTDSP1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CTDSP1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The CTDSP1 polyclonal antibody (Cat # PAB4149) is used in Western blot to detect CTDSP1 in CEM cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with CTDSP1 polyclonal antibody (Cat # PAB4149) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CTDSP1
Entrez GeneID
58190Protein Accession#
NP_067021;Q9GZU7Gene Name
CTDSP1
Gene Alias
NLIIF, SCP1
Gene Description
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Omim ID
605323Gene Ontology
HyperlinkGene Summary
RNA polymerase II
Other Designations
nuclear LIM interactor-interacting factor|small CTD phosphatase 1
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Interactome
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Disease
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Publication Reference
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Small CTD phosphatases function in silencing neuronal gene expression.
Yeo M, Lee SK, Lee B, Ruiz EC, Pfaff SL, Gill GN.
Science 2005 Jan; 307(5709):596.
Application:ChIP, WB, Human, Mouse, HEK 293, P19 cells.
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Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system.
Fernandes AO, Campagnoni CW, Kampf K, Feng JM, Handley VW, Schonmann V, Bongarzone ER, Reyes S, Campagnoni AT.
Journal of Neuroscience Research 2004 Feb; 75(4):461.
Application:IF, IHC, IP, WB, Mouse, Mouse brains, Mouse primary cerebellar granule cell cultures, Recombinant protein.
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A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5.
Yeo M, Lin PS, Dahmus ME, Gill GN.
The Journal of Biological Chemistry 2003 Jul; 278(28):26078.
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Small CTD phosphatases function in silencing neuronal gene expression.
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