PPM1G polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PPM1G.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human PPM1G.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
The PPM1G polyclonal antibody (Cat # PAB4114) is used in Western blot to detect PPM1G in CHO cell lysate (Lane 1) and mouse heart tissue lysate (Lane 2) .Enzyme-linked Immunoabsorbent Assay
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Gene Info — PPM1G
Entrez GeneID
5496Protein Accession#
O15355Gene Name
PPM1G
Gene Alias
MGC1675, MGC2870, PP2CG, PP2CGAMMA, PPP2CG
Gene Description
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Omim ID
605119Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
OTTHUMP00000123426|PP2C, gamma|protein phosphatase 1C|protein phosphatase 1G|protein phosphatase 2, catalytic subunit, gamma isoform|protein phosphatase 2C gamma isoform|protein phosphatase magnesium-dependent 1 gamma
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Interactome
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Disease
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