PTPRG polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The PTPRG polyclonal antibody (Cat # PAB4092) is used in Western blot to detect PTPRG in mouse brain tissue lysate.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PTPRG.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human PTPRG.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
The PTPRG polyclonal antibody (Cat # PAB4092) is used in Western blot to detect PTPRG in mouse brain tissue lysate.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PTPRG
Entrez GeneID
5793Protein Accession#
P23470Gene Name
PTPRG
Gene Alias
HPTPG, PTPG, R-PTP-GAMMA, RPTPG
Gene Description
protein tyrosine phosphatase, receptor type, G
Omim ID
176886Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq
Other Designations
H_RG317H01.1|protein tyrosine phosphatase gamma|protein tyrosine phosphatase, receptor type, gamma polypeptide|receptor type protein tyrosine phosphatase gamma|receptor tyrosine phosphatase gamma|receptor-type protein phosphatase gamma
-
Interactome
-
Disease
-
Publication Reference
-
Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents.
Liu S, Kulp SK, Sugimoto Y, Jiang J, Chang HL, Lin YC.
Breast Cancer Research and Treatment 2002 Jan; 71(1):21.
Application：IHC, Human, Human breast cancer.
-
Structure of the human receptor tyrosine phosphatase gamma gene (PTPRG) and relation to the familial RCC t(3;8) chromosome translocation.
Kastury K, Ohta M, Lasota J, Moir D, Dorman T, LaForgia S, Druck T, Huebner K.
Genomics 1996 Mar; 32(2):225.
Application：IHC, WB-Ti, Human, Human renal cell carcinoma.
-
Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases.
Barnea G, Silvennoinen O, Shaanan B, Honegger AM, Canoll PD, D'Eustachio P, Morse B, Levy JB, Laforgia S, Huebner K, et al..
Molecular and Cellular Biology 1993 Mar; 13(3):1497.
-
Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com