dcr-1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of dcr-1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of C.elegans dcr-1.
Host
Rabbit
Reactivity
Nematoda
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CEM cell lysate (35 ug/lane) with dcr-1 polyclonal antibody (Cat # PAB3792). -
Gene Info — dcr-1
Entrez GeneID
176138Protein Accession#
NP_498761;P34529Gene Name
dcr-1
Gene Alias
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Gene Description
DiCer Related
Gene Ontology
HyperlinkOther Designations
DiCer Related family member (dcr-1)
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Publication Reference
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Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.
Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D Jr, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR 3rd, Mello CC.
Cell 2006 Jan; 124(2):343.
Application:IP, WB-Ti, C. elegans, C. elegans embryos.
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Processing of primary microRNAs by the Microprocessor complex.
Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ.
Nature 2004 Nov; 432(7014):231.
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The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans.
Tabara H, Yigit E, Siomi H, Mello CC.
Cell 2002 Jun; 109(7):861.
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Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.
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