EIF2B3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EIF2B3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human EIF2B3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of EIF2B3 polyclonal antibody (Cat # PAB3740) in A-375 cell line lysate. EIF2B3 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — EIF2B3
Entrez GeneID
8891Protein Accession#
CAG33566;Q9HA31Gene Name
EIF2B3
Gene Alias
EIF-2B, EIF2Bgamma
Gene Description
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Gene Ontology
HyperlinkGene Summary
subunit 3 gamma
Other Designations
OTTHUMP00000010262|eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD)|eukaryotic translation initiation factor 2B, subunit 3 gamma
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Interactome
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Disease
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Publication Reference
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Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach.
Kruger M, Beger C, Li QX, Welch PJ, Tritz R, Leavitt M, Barber JR, Wong-Staal F.
PNAS 2000 Jul; 97(15):8566.
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Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.
Gomez E, Pavitt GD.
Molecular and Cellular Biology 2000 Jun; 20(11):3965.
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Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach.
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