IL28A polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
The IL28A polyclonal antibody (Cat # PAB3664) is used in Western blot to detect IL28A in mouse brain tissue lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL28A.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human IL28A.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The IL28A polyclonal antibody (Cat # PAB3664) is used in Western blot to detect IL28A in mouse brain tissue lysate. -
Gene Info — IL28A
Entrez GeneID
282616Protein Accession#
NP_742150;Q8IZJ0Gene Name
IL28A
Gene Alias
IFNL2, IL-28A
Gene Description
interleukin 28A (interferon, lambda 2)
Omim ID
607401Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq
Other Designations
interferon lambda 2|interferon-lambda 2|interleukin 28A
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Interactome
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Pathway
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Disease
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Publication Reference
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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.
Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP.
Nature Immunology 2003 Jan; 4(1):69.
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IL-28, IL-29 and their class II cytokine receptor IL-28R.
Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM.
Nature Immunology 2003 Jan; 4(1):63.
Application：Func, Monkey, COS-7 cells.
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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.
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