RIPK4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RIPK4.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human RIPK4.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of RIPK4 polyclonal antibody (Cat # PAB3477) in mouse kidney tissue lysate (35 ug/lane). RIPK4 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with RIPK4 polyclonal antibody (Cat # PAB3477) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. -
Gene Info — RIPK4
Entrez GeneID
54101Protein Accession#
P57078Gene Name
RIPK4
Gene Alias
ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4
Gene Description
receptor-interacting serine-threonine kinase 4
Omim ID
605706Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq
Other Designations
PKC-delta-interacting protein kinase|ankyrin repeat domain 3|serine/threonine-protein kinase ANKRD3
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Interactome
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Disease
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Publication Reference
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The DNA sequence of human chromosome 21.
Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park HS, Toyoda A, Ishii K, Totoki Y, Choi DK, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, Taudien S, Blechschmidt K, Polley A, Menzel U, Delabar J, Kumpf K, Lehmann R, Patterson D, Reichwald K, Rump A, Schillhabel M, Schudy A, Zimmermann W, Rosenthal A, Kudoh J, Schibuya K, Kawasaki K, Asakawa S, Shintani A, Sasaki T, Nagamine K, Mitsuyama S, Antonarakis SE, Minoshima S, Shimizu N, Nordsiek G, Hornischer K, Brant P, Scharfe M, Schon O, De
Nature 2000 May; 405(6784):311.
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The DNA sequence of human chromosome 21.
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