The BTK polyclonal antibody (Cat # PAB3419) is used in Western blot to detect BTK in Ramos cell lysate.
Western Blot (Transfected lysate)
Western blot analysis of BTK polyclonal antibody (Cat # PAB3419) transiently transfected HEK293 cell line lysate (1 ug/lane). BTK polyclonal antibody (arrow) was detected using the purified polyclonal antibody (1 : 1500 dilution).
Formalin-fixed and paraffin-embedded human cancer tissue reacted with BTK polyclonal antibody (Cat # PAB3419) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq