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Last updated: 2014/9/1
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TGIF1 polyclonal antibody

  • Catalog # : PAB2851
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TGIF1.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to internal region of human TGIF1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TGIF1 polyclonal antibody (Cat # PAB2851) in Y-79 cell line lysates (35 ug/lane). TGIF1 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7050
  • Protein Accession#:
  • NP_003235;Q15583
  • Gene Name:
  • TGIF1
  • Gene Alias:
  • HPE4,MGC39747,MGC5066,TGIF
  • Gene Description:
  • TGFB-induced factor homeobox 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. [provided by RefSeq
  • Other Designations:
  • 5'-TG-3' interacting factor,TALE homeobox TG-interacting factor,TG-interacting factor,homeobox protein TGIF,transforming growth factor-beta-induced factor
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