MYH9 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MYH9.
Immunogen
Recombinant protein corresponding to amino acids of human MYH9
Sequence
REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDF
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:1000-1:2500)
Immunofluorescence(1-4 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with MYH9 polyclonal antibody (Cat # PAB28470) shows distinct cytoplasmic positivity in cells in glomeruli.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with MYH9 polyclonal antibody (Cat # PAB28470) at 1-4 ug/ml shows positivity in plasma membrane, cytoplasm & cytoskeleton (actin filaments). -
Gene Info — MYH9
Entrez GeneID
4627Protein Accession#
P35579Gene Name
MYH9
Gene Alias
DFNA17, EPSTS, FTNS, MGC104539, MHA, NMHC-II-A, NMMHCA
Gene Description
myosin, heavy chain 9, non-muscle
Gene Ontology
HyperlinkGene Summary
This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq
Other Designations
MYH9 variant protein|OTTHUMP00000028706|cellular myosin heavy chain, type A|myosin, heavy polypeptide 9, non-muscle|non-muscle myosin heavy chain|non-muscle myosin heavy polypeptide 9|nonmuscle myosin heavy chain II-A
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Interactome
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Disease
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