ABCB6 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with ABCB6 polyclonal antibody (Cat # PAB28205) shows moderate cytoplasmic positivity in cells in tubules at 1:10-1:20 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ABCB6.
Immunogen
Recombinant protein corresponding to amino acids of recombinant ABCB6.
Sequence
STVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with ABCB6 polyclonal antibody (Cat # PAB28205) shows moderate cytoplasmic positivity in cells in tubules at 1:10-1:20 dilution. -
Gene Info — ABCB6
Entrez GeneID
10058Protein Accession#
Q9NP58Gene Name
ABCB6
Gene Alias
ABC, ABC14, EST45597, FLJ22414, MTABC3, PRP, umat
Gene Description
ATP-binding cassette, sub-family B (MDR/TAP), member 6
Omim ID
605452Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. [provided by RefSeq
Other Designations
ATP-binding cassette half-transporter|ATP-binding cassette, sub-family B, member 6
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Interactome
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Pathway
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Disease
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