ACAN polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human cartilage tissue with ACAN polyclonal antibody (Cat # PAB27837). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ACAN.
Immunogen
A synthetic peptide corresponding to 16 amino acid at C-terminus of human ACAN.
Host
Rabbit
Reactivity
Hamster, Human, Monkey, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except REG1A (50%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human cartilage tissue with ACAN polyclonal antibody (Cat # PAB27837). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — ACAN
Entrez GeneID
176Protein Accession#
P16112Gene Name
ACAN
Gene Alias
AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK
Gene Description
aggrecan
Gene Ontology
HyperlinkGene Summary
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq
Other Designations
aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)|aggrecan proteoglycan|cartilage-specific proteoglycan core protein|chondroitin sulfate proteoglycan 1|large aggregating proteo
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Interactome
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Disease
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