GAB1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GAB1.
Immunogen
A synthetic peptide corresponding to residues surrounding Y627 of human GAB1.
Sequence
V-E-Yp-L-D
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HUVEC cells untreated or treated with EGF (200 ng/mL, 15 min) using GAB1 polyclonal antibody (Cat # PAB26803).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using GAB1 polyclonal antibody (Cat # PAB26803). -
Gene Info — GAB1
Entrez GeneID
2549Protein Accession#
Q13480Gene Name
GAB1
Gene Alias
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Gene Description
GRB2-associated binding protein 1
Omim ID
604439Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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