CNR1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CNR1.
Immunogen
A synthetic peptide corresponding to 16 amino acids at C-terminus of human CNR1.
Host
Rabbit
Reactivity
Bovine, Dog, Horse, Human, Monkey, Mouse, Pig, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-8 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain, neuron with CNR1 polyclonal antibody (Cat # PAB26122).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunocytochemistry
Immunocytochemical staining of HEK293 human embryonic kidney cells transfected (A) and untransfected (B) with CNR1. Primary antibody using CNR1 polyclonal antibody (Cat # PAB26122). -
Gene Info — CNR1
Entrez GeneID
1268Protein Accession#
P21554Gene Name
CNR1
Gene Alias
CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Gene Description
cannabinoid receptor 1 (brain)
Omim ID
114610Gene Ontology
HyperlinkGene Summary
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016838|OTTHUMP00000016839|OTTHUMP00000016840|central cannabinoid receptor
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