NTRK2 (phospho Y515) polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of NTRK2.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Y515 of human NTRK2.
Sequence
P-Q-Y-Fp-G
Host
Rabbit
Theoretical MW (kDa)
140
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Immunofluorescence staining of methanol-fixed HeLa cells using NTRK2 (phospho Y515) polyclonal antibody (Cat # PAB25893, red). -
Gene Info — NTRK2
Entrez GeneID
4915Protein Accession#
Q15418Gene Name
NTRK2
Gene Alias
GP145-TrkB, TRKB
Gene Description
neurotrophic tyrosine kinase, receptor, type 2
Omim ID
600456Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BDNF/NT-3 growth factors receptor|OTTHUMP00000021573|OTTHUMP00000021574|OTTHUMP00000021575|OTTHUMP00000021576|OTTHUMP00000021577|tyrosine kinase receptor B
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Disease
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