EPM2A polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of EPM2A in SW480 cell lysate with EPM2A polyclonal antibody (Cat # PAB25630) at (1) 1 and (2) 2 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EPM2A.
Immunogen
A synthetic peptide corresponding to 17 amino acids at C-terminus of human EPM2A.
Host
Rabbit
Theoretical MW (kDa)
36
Reactivity
Human, Mouse, Rat
Specificity
At least four isoforms of EPM2A are known to exist; this antibody will detect all but the shortest isoform.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of EPM2A in SW480 cell lysate with EPM2A polyclonal antibody (Cat # PAB25630) at (1) 1 and (2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EPM2A
Entrez GeneID
7957Protein Accession#
NP_005661Gene Name
EPM2A
Gene Alias
EPM2, MELF
Gene Description
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
Gene Ontology
HyperlinkGene Summary
This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000017360|epilepsy, progressive myoclonus type 2, Lafora disease (laforin)|laforin
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Interactome
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Disease
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