TXN2 polyclonal antibody
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TXN2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human TXN2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TXN2 polyclonal antibody (Cat # PAB2468) in 293 cell line lysate (35 ug/lane). TXN2 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — TXN2
Entrez GeneID
25828Protein Accession#
NP_036605;Q99757Gene Name
TXN2
Gene Alias
MT-TRX, MTRX, TRX2
Gene Description
thioredoxin 2
Omim ID
609063Gene Ontology
HyperlinkGene Summary
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq
Other Designations
mitochondrial thioredoxin
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Interactomes
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Diseases
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Publication Reference
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Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death.
Damdimopoulos AE, Miranda-Vizuete A, Pelto-Huikko M, Gustafsson JA, Spyrou G.
The Journal of Biological Chemistry 2002 Sep; 277(36):33249.
Application:IHC-P, WB-Tr, Human, HEK 293 cells, Stomach, Colon, Kidney,Heart, Arteries, Veins, Prostate.
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Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells.
Chen Y, Cai J, Murphy TJ, Jones DP.
The Journal of Biological Chemistry 2002 Sep; 277(36):33242.
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Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death.
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