SH3TC2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SH3TC2.
Immunogen
Recombinant protein corresponding to amino acids of human SH3TC2.
Sequence
SVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SH3TC2 polyclonal antibody (Cat # PAB23149).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with SH3TC2 polyclonal antibody (Cat # PAB23149) shows strong nucleolar positivity in Purkinje cells. -
Gene Info — SH3TC2
Entrez GeneID
79628Protein Accession#
Q8TF17Gene Name
SH3TC2
Gene Alias
CMT4C, FLJ13605, KIAA1985
Gene Description
SH3 domain and tetratricopeptide repeats 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons. [provided by RefSeq
Other Designations
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Disease
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