ABCB7 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung with ABCB7 polyclonal antibody (Cat # PAB22645) shows strong membranous positivity in alveolar cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with ABCB7 polyclonal antibody (Cat # PAB22645) at 1-4 ug/mL dilution shows positivity in cytoplasm and mitochondria.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ABCB7.
Immunogen
Recombinant protein corresponding to amino acids of human ABCB7.
Sequence
GAMKDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKWEAKKENISKEEERKKLQEEI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung with ABCB7 polyclonal antibody (Cat # PAB22645) shows strong membranous positivity in alveolar cells.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with ABCB7 polyclonal antibody (Cat # PAB22645) at 1-4 ug/mL dilution shows positivity in cytoplasm and mitochondria. -
Gene Info — ABCB7
Entrez GeneID
22Protein Accession#
O75027Gene Name
ABCB7
Gene Alias
ABC7, ASAT, Atm1p, EST140535
Gene Description
ATP-binding cassette, sub-family B (MDR/TAP), member 7
Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq
Other Designations
ATP-binding cassette 7|ATP-binding cassette, sub-family B, member 7|OTTHUMP00000023578
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Interactome
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Pathway
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