FBXL11 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FBXL11.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human FBXL11.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
Immunohistochemsitry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot analysis of FBXL11 (arrow) using rabbit FBXL11 polyclonal antibody (Cat # PAB2222). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JHDM1a/FBXL11 gene (Lane 2) (Origene Technologies).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human testis tissue reacted with FBXL11 polyclonal antibody (Cat # PAB2222) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. -
Gene Info — FBXL11
Entrez GeneID
22992Protein Accession#
NP_036440;Q9Y2K7Gene Name
FBXL11
Gene Alias
CXXC8, DKFZp434M1735, FBL11, FBL7, FLJ00115, FLJ46431, JHDM1A, KDM2A, KIAA1004, LILINA
Gene Description
F-box and leucine-rich repeat protein 11
Omim ID
605657Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
F-box protein FBL11|jumonji C domain-containing histone demethylase 1A
-
Interactomes
-
Publication Reference
-
Histone demethylation by a family of JmjC domain-containing proteins.
Tsukada Y, Fang J, Erdjument-Bromage H, Warren ME, Borchers CH, Tempst P, Zhang Y.
Nature 2006 Feb; 439(7078):811.
-
Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M.
Nature 2005 Jan; 433(7021):77.
-
Histone demethylation by a family of JmjC domain-containing proteins.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com