AFP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native AFP.
Immunogen
Native purified human AFP.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to AFP. No cross-reactivity with human Albumin, CEA, Ferritin, hCG, PAP, and PSA.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Native Purified Protein.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 15 mM KPO4 buffer, 0.85% NaCl, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Sandwich ELISA
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Gene Info — AFP
Entrez GeneID
174Gene Name
AFP
Gene Alias
FETA, HPAFP
Gene Description
alpha-fetoprotein
Omim ID
104150Gene Ontology
HyperlinkGene Summary
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq
Other Designations
OTTHUMP00000160480|alpha-1-fetoprotein|alpha-fetoglobulin
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Interactome
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Disease
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Publication Reference
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An Oxygen-Concentration-Controllable Multiorgan Microfluidic Platform for Studying Hypoxia-Induced Lung Cancer-Liver Metastasis and Screening Drugs.
Lulu Zheng, Bo Wang, Yunfan Sun, Bo Dai, Yongfeng Fu, Yule Zhang, Yuwen Wang, Zhijin Yang, Zhen Sun, Songlin Zhuang, Dawei Zhang.
ACS Sensors 2021 Mar; 6(3):823.
Application:IF, Human, A-549 cells.
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A universal and enzyme-free immunoassay platform for biomarker detection based on gold nanoparticle enumeration with a dark-field microscope.
Wu X, Li T, Tao G, Lin R, Pei X, Liu F, Li N.
The Analyst 2017 Nov; 142(22):4201.
Application:Quant, Alphafeto protein.
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An Oxygen-Concentration-Controllable Multiorgan Microfluidic Platform for Studying Hypoxia-Induced Lung Cancer-Liver Metastasis and Screening Drugs.
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