ASGR1 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with ASGR1 polyclonal antibody (Cat # PAB20573).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with ASGR1 polyclonal antibody (Cat # PAB20573) shows strong positivity in hepatocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ASGR1.
Immunogen
Recombinant protein corresponding to amino acids of human ASGR1.
Sequence
MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with ASGR1 polyclonal antibody (Cat # PAB20573).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with ASGR1 polyclonal antibody (Cat # PAB20573) shows strong positivity in hepatocytes. -
Gene Info — ASGR1
Entrez GeneID
432Protein Accession#
P07306Gene Name
ASGR1
Gene Alias
HL-1, ASGPR, ASGPR1, CLEC4H1
Gene Description
asialoglycoprotein receptor 1
Omim ID
108360Gene Ontology
HyperlinkGene Summary
Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. [provided by RefSeq
Other Designations
C-type lectin domain family 4, member H1|hepatic lectin H1
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