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IMPDH2 polyclonal antibody

  • Catalog # : PAB19702
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of IMPDH2.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human IMPDH2.
  • Sequence:
  • KEEEHDCFLEEI
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 55.8
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • IMPDH2 polyclonal antibody (Cat # PAB19702) (1 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3615
  • Gene Name:
  • IMPDH2
  • Gene Alias:
  • IMPD2,IMPDH-II
  • Gene Description:
  • IMP (inosine monophosphate) dehydrogenase 2
  • Gene Summary:
  • This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq
  • Other Designations:
  • IMP dehydrogenase 2,IMP oxireductase 2,inosine 5' phosphate dehydrogenase 2,inosine monophosphate dehydrogenase 2,inosine monophosphate dehydrogenase type II,inosine monophosphate oxireductase 2
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