BCL2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic protein of BCL2.
Immunogen
Synthetic protein corresponding to human BCL2.
Host
Rabbit
Reactivity
Human, Mouse, Rabbit, Rat
Form
Lyophilized
Purification
Protein G purification
Recommend Usage
ELISA (1-2 ug/mL)
Western Blot (2-10 ug/mL)
Immunohistochemistry (2-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS.
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Immunohistochemiacl staining of mouse hippocampus with BCL2 polyclonal antibody (Cat # PAB19562 ).Immunohistochemistry
A. Immunohistochemiacl staining of rabbit hippocampus tissue section with BCL2 polyclonal antibody (Cat # PAB19562 ) at 1:200 dilution.
B. Immunohistochemiacl staining of human endometrial tissue tissue section with BCL2 polyclonal antibody (Cat # PAB19562 ) at 1:500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — BCL2
Entrez GeneID
596Protein Accession#
P10415Gene Name
BCL2
Gene Alias
Bcl-2
Gene Description
B-cell CLL/lymphoma 2
Omim ID
151430Gene Ontology
HyperlinkGene Summary
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq
Other Designations
B-cell lymphoma protein 2|OTTHUMP00000163680
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Interactome
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Pathway
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Disease
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Publication Reference
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MiR-9 functions as a tumor suppressor in acute myeloid leukemia by targeting CX chemokine receptor 4.
Zhu B, Xi X, Liu Q, Cheng Y, Yang H.
American Journal of Translational Research 2019 Jun; 11(6):3384.
Application:WB-Ce, WB-Tr, Human, CD34+ cells, HL-60, KG-1a, Kasumi-1, NB4, SKNO-1 cells, Human bone marrow.
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Protective Effect of Proanthocyanidins from Sea Buckthorn (Hippophae Rhamnoides L.) Seed against Visible Light-Induced Retinal Degeneration in Vivo.
Wang Y, Zhao L, Huo Y, Zhou F, Wu W, Lu F, Yang X, Guo X, Chen P, Deng Q, Ji B.
Nutrients 2016 May; 8(5):E245.
Application:WB-Ti, Rabbit, Rabbit retina.
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MiR-9 functions as a tumor suppressor in acute myeloid leukemia by targeting CX chemokine receptor 4.
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