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BAX polyclonal antibody

  • Catalog # : PAB19559
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic protein of BAX.
  • Immunogen:
  • Synthetic protein corresponding to human BAX.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Human, Mouse, Pig, Rat, Sheep
  • Form:
  • Lyophilized
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1-2 ug/mL)
    Western Blot (2-10 ug/mL)
    Immunohistochemistry (2-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS.
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Immunohistochemiacl staining of mouse hippocampus with BAX polyclonal antibody (Cat # PAB19559 ).
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemiacl staining of mouse hippocampus tissue section with BAX polyclonal antibody (Cat # PAB19559 ) at 1:200 dilution.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 581
  • Gene Name:
  • BAX
  • Gene Alias:
  • BCL2L4
  • Gene Description:
  • BCL2-associated X protein
  • Gene Summary:
  • The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
  • Other Designations:
  • apoptosis regulator BAX
  • Interactome
  • Interactome
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