DKK1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of whole cell lysates with DKK1 polyclonal antibody (Cat # PAB19539).
Lane 1 : U-87
Lane 2 : MCF-7
Lane 3 : A-549
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DKK1.
Immunogen
A synthetic peptide corresponding to amino acids at N-terminus of human DKK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
The synthetic peptide different from the related mouse and rat sequence by two amino acids.
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of whole cell lysates with DKK1 polyclonal antibody (Cat # PAB19539).
Lane 1 : U-87
Lane 2 : MCF-7
Lane 3 : A-549 -
Gene Info — DKK1
Entrez GeneID
22943Gene Name
DKK1
Gene Alias
DKK-1, SK
Gene Description
dickkopf homolog 1 (Xenopus laevis)
Omim ID
605189Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq
Other Designations
OTTHUMP00000019617|dickkopf homolog 1|dickkopf related protein-1|dickkopf-1 like
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Interactome
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Pathway
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Disease
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