PIAS1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of human kidney tissue with PIAS1 polyclonal antibody (Cat # PAB19242) at 1 ug/mL in (Lane 1) the absence and (Lane 2) the presence of blocking peptide.
Immunohistochemistry
Immunohistochemical staining of rat kidney tissue with PIAS1 polyclonal antibody (Cat # PAB19242) at 5 ug/mL dilution.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of PIAS1.
Immunogen
A synthetic peptide corresponding to 15 amino acids near C-terminus of human PIAS1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human kidney tissue with PIAS1 polyclonal antibody (Cat # PAB19242) at 1 ug/mL in (Lane 1) the absence and (Lane 2) the presence of blocking peptide.Immunohistochemistry
Immunohistochemical staining of rat kidney tissue with PIAS1 polyclonal antibody (Cat # PAB19242) at 5 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PIAS1
Entrez GeneID
8554Protein Accession#
NP_057250Gene Name
PIAS1
Gene Alias
DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3
Gene Description
protein inhibitor of activated STAT, 1
Omim ID
603566Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq
Other Designations
AR interacting protein|DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1|protein inhibitor of activated STAT-1|zinc finger, MIZ-type containing 3
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Interactome
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Pathway
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Disease
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