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- Home > Products > Polyclonal Ab > Human > Cytokine > LEFTY2 polyclonal antibody
LEFTY2 polyclonal antibody
- Catalog # : PAB1921
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- 100 ug
- USD $ 319
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LEFTY2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human LEFTY2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A.Genome Res. 2003 Oct;13(10):2265-70. Epub 2003 Sep 15.
- 2.
- Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes.
Yashiro K, Saijoh Y, Sakuma R, Tada M, Tomita N, Amano K, Matsuda Y, Monden M, Okada S, Hamada H.Genes Cells. 2000 May;5(5):343-57.
- 3.
- Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.
Kosaki K, Bassi MT, Kosaki R, Lewin M, Belmont J, Schauer G, Casey B.Am J Hum Genet. 1999 Mar;64(3):712-21.
- Entrez GeneID:
- 7044
- Protein Accession#:
- NP_003231;O00292
- Gene Name:
- LEFTY2
- Gene Alias:
- EBAF,LEFTA,LEFTYA,MGC46222,TGFB4
- Gene Description:
- left-right determination factor 2
- Omim ID:
- 601877
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000035570,endometrial bleeding associated factor,endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily),transforming growth factor, beta-4 (endometrial bleeding-associated factor;
- Gene Pathway
