TGFB1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant TGFB1.
Immunogen
Recombinant protein corresponding to 120 amino acids at N-terminus of human TGFB1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
ELISA (1:160000)
Western Blot (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human heart tissue showing cytoplasmic staining with TGFB1 polyclonal antibody (Cat # PAB18904) at 1 : 100 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TGFB1
Entrez GeneID
7040Protein Accession#
NM_000660Gene Name
TGFB1
Gene Alias
CED, DPD1, TGFB, TGFbeta
Gene Description
transforming growth factor, beta 1
Gene Ontology
HyperlinkGene Summary
TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM
Other Designations
TGF-beta 1 protein|diaphyseal dysplasia 1, progressive|transforming growth factor-beta 1
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Interactome
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