DICER1 polyclonal antibody
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DICER1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human DICER1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
ELISA (1:1000-1:10000)
Immunohistochemistry (1:100-1:500)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human brain tissue showing cytoplasmic staining with DICER1 polyclonal antibody (Cat # PAB18859) at 1 : 100 dilution.Immunofluorescence
Immunofluorescent staining of HeLa cells showing cytoplasmic staining with DICER1 polyclonal antibody (Cat # PAB18859) at 1 : 100 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DICER1
Entrez GeneID
23405Protein Accession#
NP_803187Gene Name
DICER1
Gene Alias
DCR1, Dicer, HERNA, KIAA0928
Gene Description
dicer 1, ribonuclease type III
Omim ID
606241Gene Ontology
HyperlinkGene Summary
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
Dicer1, Dcr-1 homolog|K12H4.8-LIKE|dicer 1, double-stranded RNA-specific endoribonuclease|dicer1|helicase with RNAse motif|helicase-moi
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