ALPI polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ALPI.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human ALPI.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ALPI polyclonal antibody (Cat # PAB1882) in HL-60 cell line lysates (35 ug/lane). ALPI (arrow) was detected using the purified polyclonal antibody. -
Gene Info — ALPI
Entrez GeneID
248Protein Accession#
NP_001622;P09923Gene Name
ALPI
Gene Alias
IAP
Gene Description
alkaline phosphatase, intestinal
Omim ID
171740Gene Ontology
HyperlinkGene Summary
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is upregulated during small intestinal epithelial cell differentiation. [provided by RefSeq
Other Designations
Kasahara isozyme|alkaline phosphomonoesterase|glycerophosphatase|intestinal alkaline phosphatase
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Interactomes
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Pathways
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Publication Reference
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A new approach using tissue alkaline phosphatase histochemistry to identify Crohn's disease.
Torres MI, Lorite P, Lopez-Casado MA, Rios A.
Pathology, Research and Practice 2007 May; 203(6):485.
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Differentiation-dependent activation of the human intestinal alkaline phosphatase promoter by HNF-4 in intestinal cells.
Olsen L, Bressendorff S, Troelsen JT, Olsen J.
American Journal of Physiology. Gastrointestinal and Liver Physiology 2005 Aug; 289(2):G220.
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Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2.
Alkhoury F, Malo MS, Mozumder M, Mostafa G, Hodin RA.
American Journal of Physiology. Gastrointestinal and Liver Physiology 2005 Aug; 289(2):G285.
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A new approach using tissue alkaline phosphatase histochemistry to identify Crohn's disease.
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