ALDH3A1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
ALDH3A1 polyclonal antibody (Cat # PAB18542) (0.01 ug/mL) staining of mouse eye lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung with ALDH3A1 polyclonal antibody (Cat # PAB18542) (3.8 ug/mL). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ALDH3A1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human ALDH3A1.
Sequence
C-RYPPSPAKMTQH
Host
Goat
Theoretical MW (kDa)
55
Reactivity
Human, Mouse
Specificity
Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(3-5 ug/mL)
ELISA (1:32000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ALDH3A1 polyclonal antibody (Cat # PAB18542) (0.01 ug/mL) staining of mouse eye lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lung with ALDH3A1 polyclonal antibody (Cat # PAB18542) (3.8 ug/mL). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ALDH3A1
Entrez GeneID
218Protein Accession#
NP_000682.3Gene Name
ALDH3A1
Gene Alias
ALDH3, ALDHIII, MGC10406
Gene Description
aldehyde dehydrogenase 3 family, memberA1
Omim ID
100660Gene Ontology
HyperlinkGene Summary
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
aldehyde dehydrogenase 3A1|aldehyde dehydrogenase isozyme 3|aldehyde dehydrogenase type III|aldehyde dehydrogenase, dimeric NADP-preferring|stomach aldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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