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Last updated: 2014/10/20
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ALDH2 polyclonal antibody

  • Catalog # : PAB18541
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of ALDH2.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human ALDH2.
  • Sequence:
  • C-DETQFKKILGYIN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 50
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Sandwhich ELISA (1-2 ug/mL)
    Western Blot (0.03-0.1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • ALDH2 polyclonal antibody (Cat # PAB18541) (0.03 ug/mL) staining of mouse liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Sandwich ELISA
  • Sandwich ELISA
  • ALDH2 polyclonal antibody (Cat # PAB18541) (1.5 ug/mL) as the reporter with the capture rabbit antibody (2.5 ug/mL).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 217
  • Gene Name:
  • ALDH2
  • Gene Alias:
  • ALDH-E2,ALDHI,ALDM,MGC1806
  • Gene Description:
  • aldehyde dehydrogenase 2 family (mitochondrial)
  • Gene Summary:
  • This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq
  • Other Designations:
  • ALDH class 2,acetaldehyde dehydrogenase 2,liver mitochondrial ALDH,mitochondrial aldehyde dehydrogenase 2,nucleus-encoded mitochondrial aldehyde dehydrogenase 2
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