DNMT1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DNMT1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human DNMT1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The DNMT1 polyclonal antibody (Cat # PAB1833) is used in Western blot to detect DNMT1 in Jurkat cell lysate. -
Gene Info — DNMT1
Entrez GeneID
1786Protein Accession#
NP_001370;P26358Gene Name
DNMT1
Gene Alias
AIM, CXXC9, DNMT, FLJ16293, MCMT, MGC104992
Gene Description
DNA (cytosine-5-)-methyltransferase 1
Omim ID
126375Gene Ontology
HyperlinkGene Summary
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CXXC finger protein 9|DNA methyltransferase 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells.
Li G, Weyand CM, Goronzy JJ.
Journal of Leukocyte Biology 2008 Jun; 84(3):824.
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Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells.
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