CSF2RB polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CSF2RB.
Immunogen
A synthetic peptide corresponding to human CSF2RB.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl (0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HepG2 cells using CSF2RB polyclonal antibody (Cat # PAB18157).
Peptide "+" means "peptide blocking".Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CSF2RB
Entrez GeneID
1439Protein Accession#
P32927Gene Name
CSF2RB
Gene Alias
CD131, CDw131, IL3RB, IL5RB
Gene Description
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq
Other Designations
GM-CSF/IL-3/IL-5 receptor common beta-chain|colony stimulating factor 2 receptor, beta|colony-stimulating factor-2 receptor, beta, low-affinity|cytokine receptor common subunit beta|interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3
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Interactome
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Pathway
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Disease
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Publication Reference
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Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia.
Le Beau MM, Davis EM, Patel B, Phan VT, Sohal J, Kogan SC.
Blood 2003 Aug; 102(3):1072.
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The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger protein.
McLoughlin P, Ehler E, Carlile G, Licht JD, Schafer BW.
The Journal of Biological Chemistry 2002 Oct; 277(40):37045.
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Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia.
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