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Last updated: 2014/9/15
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ACAN polyclonal antibody

  • Catalog # : PAB18067
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ACAN .
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 336-369 of human ACAN.
  • Sequence:
  • FFGVGGEED
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is specific to endogenous levels of fragment of activated ACAN resulting from cleavage adjacent to Asp369.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500~1:1000)
    Immunohistochemistry (1:50~1:100)
    ELISA(1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from Jurkat cells, treated with Etoposide (25 uM, 60 mins), using ACAN polyclonal antibody (Cat # PAB18067).
    Peptide "+" means "with peptide blocking".
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using ACAN polyclonal antibody (Cat # PAB18067).
    Peptide "+" means "with peptide blocking".
  • Immunohistochemistry
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 176
  • Gene Name:
  • ACAN
  • Gene Alias:
  • AGC1,AGCAN,CSPG1,CSPGCP,MSK16,SEDK
  • Gene Description:
  • aggrecan
  • Gene Summary:
  • This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq
  • Other Designations:
  • aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122),aggrecan proteoglycan,cartilage-specific proteoglycan core protein,chondroitin sulfate proteoglycan 1,large aggregating proteo
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