FIGF polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of whole cell lysats with FIGF polyclonal antibody (Cat # PAB17217).
Lane 1 : SW620 whole cell lysate.
Lane 2 : Colo 320 whole cell lysate.
Lane 3 : 6T-CEM whole cell lysate.
Lane 4 : HT1080 whole cell lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FIGF.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human FIGF.
Host
Rabbit
Reactivity
Human
Specificity
The synthetic peptide of this antibody is identical to the related rat sequence.
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of whole cell lysats with FIGF polyclonal antibody (Cat # PAB17217).
Lane 1 : SW620 whole cell lysate.
Lane 2 : Colo 320 whole cell lysate.
Lane 3 : 6T-CEM whole cell lysate.
Lane 4 : HT1080 whole cell lysate. -
Gene Info — FIGF
Entrez GeneID
2277Gene Name
FIGF
Gene Alias
VEGF-D, VEGFD
Gene Description
c-fos induced growth factor (vascular endothelial growth factor D)
Omim ID
300091Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. [provided by RefSeq
Other Designations
OTTHUMP00000022960|vascular endothelial growth factor D
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Interactome
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Pathway
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Disease
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Publication Reference
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VEGF-D promotes the metastatic spread of tumor cells via the lymphatics.
Stacker SA, Caesar C, Baldwin ME, Thornton GE, Williams RA, Prevo R, Jackson DG, Nishikawa S, Kubo H, Achen MG.
Nature Medicine 2001 Feb; 7(2):186.
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Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).
Achen MG, Jeltsch M, Kukk E, Makinen T, Vitali A, Wilks AF, Alitalo K, Stacker SA.
PNAS 1998 Jan; 95(2):548.
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Molecular cloning of a novel vascular endothelial growth factor, VEGF-D.
Yamada Y, Nezu J, Shimane M, Hirata Y.
Genomics 1997 Jun; 42(3):483.
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VEGF-D promotes the metastatic spread of tumor cells via the lymphatics.
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