Western blot analysis of cell and tissue extracts with NOS2 polyclonal antibody (Cat # PAB17215). Lane 1 : rat brain. Lane 2 : rat brain. Lane 3 : rat kidney. Lane 4 : rat heart. Lane 5 : MCF-7 cell. Lane 6 : MM453 cell. Lane 7 : SMMC cell. Lane 8 : SW620 cell.
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq