IL16 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of IL16 in rat brain tissue lysate with IL16 polyclonal antibody (Cat # PAB16687) at (A) 1 ug/mL and (B) 2 ug/mL .
Immunohistochemistry
Immunohistochemistry of IL16 in mouse brain tissue with IL16 polyclonal antibody (Cat # PAB16687) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL16.
Immunogen
A synthetic peptide corresponding to N-terminus 20 amino acids of human IL16.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of IL16 in rat brain tissue lysate with IL16 polyclonal antibody (Cat # PAB16687) at (A) 1 ug/mL and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemistry of IL16 in mouse brain tissue with IL16 polyclonal antibody (Cat # PAB16687) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL16
Entrez GeneID
3603Protein Accession#
AAQ86961Gene Name
IL16
Gene Alias
FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16
Gene Description
interleukin 16 (lymphocyte chemoattractant factor)
Omim ID
603035Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000190849|OTTHUMP00000190850|interleukin 16|lymphocyte chemoattractant factor
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Interactome
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Disease
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Publication Reference
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Interleukin-16.
Cruikshank WW, Kornfeld H, Center DM.
Journal of Leukocyte Biology 2000 Jun; 67(6):757.
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Processing and activation of pro-interleukin-16 by caspase-3.
Zhang Y, Center DM, Wu DM, Cruikshank WW, Yuan J, Andrews DW, Kornfeld H.
The Journal of Biological Chemistry 1998 Jan; 273(2):1144.
Application：IP, WB-Tr, Monkey, COS cells.
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IL-16 represses HIV-1 promoter activity.
Maciaszek JW, Parada NA, Cruikshank WW, Center DM, Kornfeld H, Viglianti GA.
The Journal of Immunology 1997 Jan; 158(1):5.
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Interleukin-16.
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