CD79A polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
A : Immunohistochemical analysis of CD79A expression in paraffin fixed mouse inguinal lymphoma tissue. CD79A polyclonal antibody (Cat ID # PAB16611) was used as primary antibody.
B : Immunohistochemical analysis of CD79A expression in paraffin fixed mouse intra abdominal lymphoma tissue. CD79A polyclonal antibody (Cat ID # PAB16611) was used as primary antibody.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CD79A.
Immunogen
Recombinant protein corresponding to human CD79A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Recommend Usage
ELISA (1-2 ug/mL)
Immunohistochemistry (2-10 ug/mL)
Western Blot (2-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS, pH 7.4.
Storage Instruction
The lyophilized antibody is stable for at least 1 year from date of receipt at -20°C.
After reconstitution with 0.01 M PBS, pH 7.4 or other diluents, this antibody can be stored in working aliquots at 2°C- 8°C for one month, or at -20°C for six months without detectable loss of activity.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
A : Immunohistochemical analysis of CD79A expression in paraffin fixed mouse inguinal lymphoma tissue. CD79A polyclonal antibody (Cat ID # PAB16611) was used as primary antibody.
B : Immunohistochemical analysis of CD79A expression in paraffin fixed mouse intra abdominal lymphoma tissue. CD79A polyclonal antibody (Cat ID # PAB16611) was used as primary antibody.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CD79A
Entrez GeneID
973Protein Accession#
P11912Gene Name
CD79A
Gene Alias
IGA, MB-1
Gene Description
CD79a molecule, immunoglobulin-associated alpha
Omim ID
112205Gene Ontology
HyperlinkGene Summary
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
B-cell antigen receptor complex-associated protein alpha chain|CD79A antigen|CD79a antigen (immunoglobulin-associated alpha)|MB-1 membrane glycoprotein|surface IgM-associated protein
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Interactome
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Pathway
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Disease
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Publication Reference
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B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice.
Li Y, Chen F, Putt M, Koo YK, Madaio M, Cambier JC, Cohen PL, Eisenberg RA.
Journal of Immunology 2008 Sep; 181(5):2961.
Application：Func, Mouse, Mouse B cells.
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Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma.
Polson AG, Yu SF, Elkins K, Zheng B, Clark S, Ingle GS, Slaga DS, Giere L, Du C, Tan C, Hongo JA, Gogineni A, Cole MJ, Vandlen R, Stephan JP, Young J, Chang W, Scales SJ, Ross S, Eaton D, Ebens A.
Blood 2007 Jul; 110(2):616.
Application：Func, Human, BJAB cells.
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B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice.
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