CD3E polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CD3E.
Immunogen
Recombinant protein corresponding to human CD3E.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Recommend Usage
ELISA (1-2 ug/mL)
Immunohistochemistry (2-10 ug/mL)
Western Blot (2-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Immunofluorescence
Immunohistochemical analysis of CD3E expressison in human colon cancer tissue CD3E polyclonal antibody (Cat ID # PAB16609) was used as primary antibody, dilution 1 : 60.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CD3E
Entrez GeneID
916Protein Accession#
P07766Gene Name
CD3E
Gene Alias
FLJ18683, T3E, TCRE
Gene Description
CD3e molecule, epsilon (CD3-TCR complex)
Omim ID
186830Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq
Other Designations
CD3-epsilon|CD3E antigen, epsilon polypeptide|CD3e antigen, epsilon polypeptide (TiT3 complex)|T-cell antigen receptor complex, epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450.
Robles-Valero J, Martin-Cofreces NB, Lamana A, Macdonald S, Volkov Y, Sanchez-Madrid F.
Blood 2010 Mar; 115(21):4174.
-
Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes.
Go YY, Zhang J, Timoney PJ, Cook RF, Horohov DW, Balasuriya UB.
Journal of Virology 2010 Mar; 84(10):4898.
-
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors.
Satoh-Takayama N, Lesjean-Pottier S, Vieira P, Sawa S, Eberl G, Vosshenrich CA, Di Santo JP.
The Journal of Experimental Medicine 2010 Feb; 207(2):273.
-
Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com