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TNF polyclonal antibody   

  • Catalog # : PAB15549
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  • 200 uL
  • USD $ 319
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against full length recombinant TNF.
  • Immunogen:
  • Recombinant protein corresponding to full length human TNF.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Primates
  • Specificity:
  • No reactivity is detected against human TNF-b (lymphotoxin). This will recognize the cell-bound precursor of TNFa as a 26,000 protein in immunoblots, particularly in denatured samples. This is also useful for neutralization of human and primate TNFa. Cross-reacts with human and other Primates.
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In antiserum
  • Storage Instruction:
  • Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Radioimmunoassay
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Radioimmunoassay
  • Gene Information
  • Entrez GeneID:
  • 7124
  • Gene Name:
  • TNF
  • Gene Alias:
  • DIF,TNF-alpha,TNFA,TNFSF2
  • Gene Description:
  • tumor necrosis factor (TNF superfamily, member 2)
  • Gene Summary:
  • This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
  • Other Designations:
  • APC1 protein,OTTHUMP00000029281,OTTHUMP00000037669,TNF superfamily, member 2,TNF, macrophage-derived,TNF, monocyte-derived,cachectin,tumor necrosis factor alpha
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