Rabbit polyclonal antibody raised against synthetic peptide of PODXL.
A synthetic peptide corresponding to amino acids 350-450 of human PODXL.
80% sequence identity with canine, 76% sequence identity with rat, and 70% sequence identity with mouse proteins. This antibody can be used for Western blot analysis. There is also a strong non-specific band at ~27 KDa.
Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq