F10 polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against F10.
Immunogen
Purified human F10.
Host
Sheep
Reactivity
Human
Specificity
This antibody has a single antigen reactivity with minimal cross reactivity with other human serum proteins.
Form
Liquid
Recommend Usage
ELISA (1:1000)
Immunodiffusion (1:32)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunocytochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Immunodiffusion
Immunoelectron Microscopy
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Gene Info — F10
Entrez GeneID
2159Gene Name
F10
Gene Alias
FX, FXA
Gene Description
coagulation factor X
Omim ID
227600Gene Ontology
HyperlinkGene Summary
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq
Other Designations
OTTHUMP00000018735|Stuart-Prower factor|factor Xa|prothrombinase
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