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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

ANXA6

Gene Alias

ANX6, CBP68

Gene Description

annexin A6

Omim ID

Gene Ontology

Gene Summary

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. [provided by RefSeq

Other Designations

annexin VI|annexin VI (p68)|calcium-binding protein p68|calelectrin|calphobindin II