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ERBB4 polyclonal antibody   

  • Catalog # : PAB14786
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  • 100 uL
  • USD $ 319
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  • Email : sales@abnova.com
    Phone : +1-909-992-0619 (new)
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ERBB4.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human ERBB4.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 185
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • Lot specific
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast cancer stained with ERBB4 polyclonal antibody (Cat # PAB14786).
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 2066
  • Gene Name:
  • ERBB4
  • Gene Alias:
  • HER4,MGC138404,p180erbB4
  • Gene Description:
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  • Gene Summary:
  • This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
  • Other Designations:
  • avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4,receptor tyrosine-protein kinase erbB-4,tyrosine kinase-type cell surface receptor HER4,v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4,v-erb-a erythroblastic leukemia v
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