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- Home > Products > Polyclonal Ab > Human > Signal Transduction > TCF7L2 polyclonal antibody
TCF7L2 polyclonal antibody
- Catalog # : PAB13547
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- 100 ug
- USD $ 319
- order now, ship in 5 days
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against full length recombinant TCF7L2.
- Immunogen:
- Recombinant protein corresponding to full length human TCF7L2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody reacts with TCF7L2.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Recommend Usage:
- Immunocytochemistry (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline.
Yang L, Bashaw GJ.Neuron. 2006 Nov 22;52(4):595-607.
- 2.
- A Ras-induced conformational switch in the Ras activator Son of sevenless.
Freedman TS, Sondermann H, Friedland GD, Kortemme T, Bar-Sagi D, Marqusee S, Kuriyan J.Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16692-7. Epub 2006 Oct 30.
- 3.
- New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.
Silver SJ, Chen F, Doyon L, Zink AW, Rebay I.Genesis. 2004 Aug;39(4):263-72.
- Application Image
- Western Blot
- Immunocytochemistry
- Immunoprecipitation
- Entrez GeneID:
- 6934
- Gene Name:
- TCF7L2
- Gene Alias:
- TCF-4,TCF4
- Gene Description:
- transcription factor 7-like 2 (T-cell specific, HMG-box)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes
- Other Designations:
- OTTHUMP00000020496,transcription factor 7-like 2
- Related Disease
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Autoimmune Diseases
- Birth Weight
- Body Weight
- Breast cancer
- Breast Neoplasms
- Calcinosis
- Carcinoma
- Cardiovascular Diseases
- Chronic Disease
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Coronary Artery Disease
- Coronary Disease
