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COL2A1 polyclonal antibody   

  • Catalog # : PAB13493
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  • 100 uL
  • USD $ 335
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against native COL2A1.
  • Immunogen:
  • Native purified COL2A1 from human cartilage.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human collagen type II, cross-reactivity with human collagen type I, and IV <1.0%, human collagens type III, V, IX and XI <0.1%, human fibronectin <0.1%.
  • Form:
  • Lyophilized
  • Recommend Usage:
  • Immunohistochemistry (1:200-1:600)
    Immunofluorescence (1:80)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at -20°C.
    Aliquot after reconstitution to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunofluorescence
  • ELISA
  • Radioimmunoassay
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunofluorescence
  • ELISA
  • Radioimmunoassay
  • Gene Information
  • Entrez GeneID:
  • 1280
  • Gene Name:
  • COL2A1
  • Gene Alias:
  • ANFH,AOM,COL11A3,MGC131516,SEDC
  • Gene Description:
  • collagen, type II, alpha 1
  • Gene Summary:
  • This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000195063,cartilage collagen,chondrocalcin,collagen II, alpha-1 polypeptide
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