CDCA8 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of CDCA8 in rat kidney tissue lysate with CDCA8 polyclonal antibody (Cat # PAB13058) at (A) 1 and (B) 2 ug/mL .
Immunofluorescence
Immunofluorescence staining of rat kidney tissue with 20 ug/mL CDCA8 polyclonal antibody (Cat # PAB13058).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDCA8.
Immunogen
A synthetic peptide corresponding to N-terminus 19 amino acids of human CDCA8.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of CDCA8 in rat kidney tissue lysate with CDCA8 polyclonal antibody (Cat # PAB13058) at (A) 1 and (B) 2 ug/mL .Immunofluorescence
Immunofluorescence staining of rat kidney tissue with 20 ug/mL CDCA8 polyclonal antibody (Cat # PAB13058). -
Gene Info — CDCA8
Entrez GeneID
55143Protein Accession#
NP_060571Gene Name
CDCA8
Gene Alias
BOR, BOREALIN, FLJ10468, FLJ12042
Gene Description
cell division cycle associated 8
Omim ID
609977Gene Ontology
HyperlinkGene Summary
CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle (Gassmann et al., 2004 [PubMed 15249581]).[supplied by OMIM
Other Designations
Dasra B|OTTHUMP00000004514|OTTHUMP00000004515
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Interactome
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Publication Reference
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Borealin is repressed in response to p53/Rb signaling.
Date DA, Jacob CJ, Bekier ME, Stiff AC, Jackson MW, Taylor WR.
Cell Biology International 2007 Dec; 31(12):1470.
Application：IF, IHC-P, Human, Human tissue array.
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Loss of Drosophila borealin causes polyploidy, delayed apoptosis and abnormal tissue development.
Hanson KK, Kelley AC, Bienz M.
Development 2005 Nov; 132(21):4777.
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Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle.
Gassmann R, Carvalho A, Henzing AJ, Ruchaud S, Hudson DF, Honda R, Nigg EA, Gerloff DL, Earnshaw WC.
The Journal of Cell Biology 2004 Jul; 166(2):179.
Application：IP, WB, Human, HeLa cells.
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Borealin is repressed in response to p53/Rb signaling.
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