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- Home > Products > Polyclonal Ab > Human > Apoptosis > BIRC2 polyclonal antibody
BIRC2 polyclonal antibody
- Catalog # : PAB12922
- Visit Frequency :
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- 100 ug
- USD $ 319
- order now, ship in 5 days
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BIRC2.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 14 amino acids of human BIRC2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- c-IAP antibody detects both c-IAP1 and c-IAP2.
- Form:
- Liquid
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2.
Li X, Yang Y, Ashwell JD.Nature. 2002 Mar 21;416(6878):345-7.
- 2.
- IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.
Deveraux QL, Roy N, Stennicke HR, Van Arsdale T, Zhou Q, Srinivasula SM, Alnemri ES, Salvesen GS, Reed JC.EMBO J. 1998 Apr 15;17(8):2215-23.
- 3.
- The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.
Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV.Cell. 1995 Dec 29;83(7):1243-52.
- Entrez GeneID:
- 329
- Protein Accession#:
- NP_001157
- Gene Name:
- BIRC2
- Gene Alias:
- API1,HIAP2,Hiap-2,MIHB,RNF48,cIAP1
- Gene Description:
- baculoviral IAP repeat-containing 2
- Omim ID:
- 601712
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq
- Other Designations:
- NFR2-TRAF signalling complex protein,apoptosis inhibitor 1,baculoviral IAP repeat-containing protein 2
